Endocrine Abstracts

Introducion: Pituitary apoplexy is an endocrine emergency that is a rare complication of pituitary adenomas and exceptional in ACTH adenomas. We report a case of apoplexy on corticotropic adenoma with intermittent secretion.Case report: The patient was 41 years old woman, she presented in 2012 a period of symptomatic hypercortisolism. Urinary free cortisol was elevated to 113 μg/24 h, Low-dose dexamethasone testing was negative, ACTH was elevated to...

Introduction: The syndrome of familial isolated pituitary adenomas (FIPA) or predisposition to pituitary adenomas (PAP) is characterized by the presence within the same family of at least 2 isolated pituitary adenomas without any other type of associated endocrine tumor. We report the case of a prolactinoma attached to the pituitary stalk as part of FIPA, revealed by erectile dysfunction.Case report: A 40 year old man presented with eretile dysfunction s...

Introduction: Fahr syndrome is a rare disease, characterized by bilateral and symmetrical intracerebral calcifications, localized in the central gray nucleus and by the classic association with hypoparathyroidism. We report a case of Fahr syndrome associated with postoperative hypoparathyroidism.Case report: A 58 year old female patient with a history of total thyroidectomy 18 years ago. She complained of chronic paresthesia, muscle cramps complicated so...

Introduction: Thyroid storm is an acute exacerbation of hyperthyroidism, responsible for significant mortality despite treatment.Case report: We report the observation of a 43-year-old diabetic patient with basedow’s disease with poor therapeutic adherence; admitted for convulsions and loss of consciousness. The diagnosis of acute thyroid storm on drop out of treatment was mentioned, in front of the detection of peripheral hyperthyroidism with low ...

IntroductionIn diabetes, lipid abnormalities are frequent and pronounced and are an important factor in increased cardiovascular risk, especially in type 2 diabetics, mostly in combination with other risk factors. The aim of this work is to highlight the prevalence of dyslipidemia in a considerable population of diabetics in Es-Smara.Patients and methodsAs part of a multidisciplinary medical caravan carried o...

IntroductionThe diabetic is characterized by his vulnerability to infections of the upper limb compared to the general population realizing the tropical diabetic hand. So this is a very serious problem, especially in emerging countries in tropical regions. The aim of this work is to study the clinical, therapeutic and progressive aspects of infections of the upper limb in diabetic patients.Materials and methods<p class="abstext...

IntroductionProlactinomas are the most frequent pituitary tumors. They are usually benign with a good response to conventional medical treatment by dopaminergic agonists (DA). However in some cases, prolactinomas are defined as invasive or aggressive according to clinical, radiological, biological and histopatholgical arguments. The aim of our case report is to discuss potential predictors of aggressiveness in prolactine secreting pituitary tumors.<p...

Background: An adrenal incidentaloma (AI) is defined as an adrenal lesion that is discovered when a radiological study is performed for indications other than suspected adrenal disease. All patients with an AI should be evaluated for endocrine adrenal functioning and malignancy potential features. A combination of pheochromocytoma and Cushing’s syndrome in same adrenal gland is extremely rare. We report a case of AI with the evidence of both pheochromocytoma and sub-clini...

Introduction: Primary aldosteronism (PA) is widely recognized as the most common form of secondary hypertension (1). PA, also known as Conn syndrome, is a group of pathological conditions associated with an aldosterone secretion inappropriate for sodium intake, that is relatively autonomous from renin–angiotensin system activity and potassium levels.Clinical Case 1: Thirty two year-old patient, diagnosed since 11 months with arterial hypertension wi...

Introduction: Paragangliomas (PGL) are rare neuroendocrine tumors of the chromaffin cells of the sympathic and parasympathic ganglia. They are responsible for catecholaminergic hypersecretion syndrome. Clinical presentation and malignant potential are variable and closely linked to the genetic profile.Clinical Case 1: Fifty three year old patient, diagnosed with diabetes and high blood pression for 4 years, she reported a Menard’s Triad evolving for...